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Reaction List for CamKII

Entries are grouped according to Reaction Name and they are alternately color coded using  and  color.
Further ordering can be done to the table header.  indicates that ordering is done according to ascending or descending order.
Keq is calculated only for first order reactions.
Kd is calculated only for second order reactions. [nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules]
  Reaction
Name
Accession Name / 
Accession No.
Pathway Name / 
Pathway No.
KfKbKdtauReagents
1 
  • Stoch_Basal_
    CaMKII_PSD
  • AMPAR_traff_
    model0

    Accession No. 59
  • CaMKII

    Pathway No. 235
    1
    (s^-1)
    1
    (s^-1)
    Keq = 1(uM)0.5sec  Substrate:
  •  basal_CaMKII_
    PSD_control


     Products:
  •  basal_CaMKII_
    PSD

  • 2 
  • Stoch_Basal_
    CaMKII_PSD
  • AMPAR_traff_
    model1

    Accession No. 60
  • CaMKII

    Pathway No. 245
    1
    (s^-1)
    1
    (s^-1)
    Keq = 1(uM)0.5sec  Substrate:
  •  basal_CaMKII_
    PSD_control


     Products:
  •  basal_CaMKII_
    PSD

  • 3 
  • Stoch_Basal_
    CaMKII_PSD
  • CaMKII_noPKA_
    model3

    Accession No. 62
  • Shared_Object_
    CaMKII_noPKA_
    model3

    Pathway No. 257
  • 1
    (s^-1)
    1
    (s^-1)
    Keq = 1(uM)0.5sec  Substrate:
  •  basal_CaMKII_
    PSD_control


     Products:
  •  basal_CaMKII_
    PSD

  • 4 
  • Stoch_Basal_
    CaMKII_PSD
  • CaMKII_model3

    Accession No. 63
  • Shared_Object_
    CaMKII_model3

    Pathway No. 263
  • 1
    (s^-1)
    1
    (s^-1)
    Keq = 1(uM)0.5sec  Substrate:
  •  basal_CaMKII_
    PSD_control


     Products:
  •  basal_CaMKII_
    PSD

  • 5 
  • Stoch_Basal_
    CaMKII_PSD
  • AMPAR_CaMKII_
    strong_coupling

    Accession No. 64
  • Shared_Object_
    AMPAR_CaMKII_
    strong_coupling

    Pathway No. 271
  • 1
    (s^-1)
    1
    (s^-1)
    Keq = 1(uM)0.5sec  Substrate:
  •  basal_CaMKII_
    PSD_control


     Products:
  •  basal_CaMKII_
    PSD

  • 6 
  • Stoch_Basal_
    CaMKII_PSD
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. 65
  • CaMKII_PSD

    Pathway No. 292
    1
    (s^-1)
    1
    (s^-1)
    Keq = 1(uM)0.5sec  Substrate:
  •  basal_CaMKII_
    PSD_control


     Products:
  •  basal_CaMKII_
    PSD

  •   This reaction comes into play when stochastic calculations are used. If we do not have a stochastic step here then the levels of basal_CaMKII_PSD are just a fixed number, which is probably not a good representation of stochasticity. Having a reaction for the basal activity ensures that the basal activity too exhibits some fluctuations.
    7 dephosp_CaMKIIICaMKIII

    Accession No. 90
  • Shared_Object_
    CaMKIII

    Pathway No. 1093
  • 0.07
    (s^-1)
    0
    (s^-1)
    --  Substrate:
     CaMKIII*

     Products:
     CaMKIII
    8 CaM_act_CaMKIIBCM

    Accession No. 96
    bcm

    Pathway No. 1118
    0.1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 1(uM)-  Substrate:
     Ca4.CaM
     CaMKII

     Products:
     act_CaMKII
    9 
  • CaMKIII_bind_
    CaM-Ca4
  • CaMKIII

    Accession No. 90
  • Shared_Object_
    CaMKIII

    Pathway No. 1093
  • 99
    (uM^-1 s^-1)
    0.09
    (s^-1)
    Kd(bf) = 0.0009(uM)-  Substrate:
     CaM-Ca4
     CaMKIII

     Products:
     CaMKIII_CaM-Ca4
    10 
  • CaMKII-thr286-bi
    nd-CaM-PSD
  • AMPAR_traff_
    model0

    Accession No. 59
  • CaMKII

    Pathway No. 235
    1000.02
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.0001(uM)-  Substrate:
  •  CaMKII-thr286-PS
    D

     CaM-Ca4-PSD

     Products:
  •  CaMKII-thr286-Ca
    M-PSD

  •   Same values as for the main compartment Can the main compartment pool of Ca/CaM be used?
    11 
  • CaMKII-thr286-bi
    nd-CaM-PSD
  • AMPAR_traff_
    model1

    Accession No. 60
  • CaMKII

    Pathway No. 245
    1000.02
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.0001(uM)-  Substrate:
  •  CaMKII-thr286-PS
    D

     CaM-Ca4-PSD

     Products:
  •  CaMKII-thr286-Ca
    M-PSD

  •   Same values as for the main compartment Can the main compartment pool of Ca/CaM be used?
    12 
  • CaMKII-thr286-bi
    nd-CaM-PSD
  • CaMKII_noPKA_
    model3

    Accession No. 62
  • Shared_Object_
    CaMKII_noPKA_
    model3

    Pathway No. 257
  • 1000.02
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.0001(uM)-  Substrate:
  •  CaMKII-thr286-PS
    D

     CaM-Ca4-PSD

     Products:
  •  CaMKII-thr286-Ca
    M-PSD

  •   Same values as for the main compartment Can the main compartment pool of Ca/CaM be used?
    13 
  • CaMKII-thr286-bi
    nd-CaM-PSD
  • CaMKII_model3

    Accession No. 63
  • Shared_Object_
    CaMKII_model3

    Pathway No. 263
  • 1000.02
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.0001(uM)-  Substrate:
  •  CaMKII-thr286-PS
    D

     CaM-Ca4-PSD

     Products:
  •  CaMKII-thr286-Ca
    M-PSD

  •   Same values as for the main compartment Can the main compartment pool of Ca/CaM be used?
    14 
  • CaMKII-thr286-bi
    nd-CaM-PSD
  • AMPAR_CaMKII_
    strong_coupling

    Accession No. 64
  • Shared_Object_
    AMPAR_CaMKII_
    strong_coupling

    Pathway No. 271
  • 1000.02
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.0001(uM)-  Substrate:
  •  CaMKII-thr286-PS
    D

     CaM-Ca4-PSD

     Products:
  •  CaMKII-thr286-Ca
    M-PSD

  •   Same values as for the main compartment Can the main compartment pool of Ca/CaM be used?
    15 
  • CaMKII-thr286-bi
    nd-CaM-PSD
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. 65
  • CaMKII_PSD

    Pathway No. 292
    1000.02
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.0001(uM)-  Substrate:
  •  CaMKII-thr286-PS
    D

     CaM-Ca4-PSD

     Products:
  •  CaMKII-thr286-Ca
    M-PSD

  •   Same values as for the main compartment Can the main compartment pool of Ca/CaM be used?
    16 CaMKII-diss-CaM
  • AMPAR_traff_
    model0

    Accession No. 59
  • CaMKII

    Pathway No. 235
    5
    (s^-1)
    0
    (uM^-1 s^-1)
    --  Substrate:
     CaMKII-CaM-PSD

     Products:
     CaM-Ca4-PSD
     CaMKII-PSD
    17 CaMKII-diss-CaM
  • AMPAR_traff_
    model1

    Accession No. 60
  • CaMKII

    Pathway No. 245
    5
    (s^-1)
    0
    (uM^-1 s^-1)
    --  Substrate:
     CaMKII-CaM-PSD

     Products:
     CaM-Ca4-PSD
     CaMKII-PSD
    18 CaMKII-diss-CaM
  • CaMKII_noPKA_
    model3

    Accession No. 62
  • Shared_Object_
    CaMKII_noPKA_
    model3

    Pathway No. 257
  • 5
    (s^-1)
    0
    (uM^-1 s^-1)
    --  Substrate:
     CaMKII-CaM-PSD

     Products:
     CaM-Ca4-PSD
     CaMKII-PSD
    19 CaMKII-diss-CaMCaMKII_model3

    Accession No. 63
  • Shared_Object_
    CaMKII_model3

    Pathway No. 263
  • 5
    (s^-1)
    0
    (uM^-1 s^-1)
    --  Substrate:
     CaMKII-CaM-PSD

     Products:
     CaM-Ca4-PSD
     CaMKII-PSD
    20 CaMKII-diss-CaM
  • AMPAR_CaMKII_
    strong_coupling

    Accession No. 64
  • Shared_Object_
    AMPAR_CaMKII_
    strong_coupling

    Pathway No. 271
  • 5
    (s^-1)
    0
    (uM^-1 s^-1)
    --  Substrate:
     CaMKII-CaM-PSD

     Products:
     CaM-Ca4-PSD
     CaMKII-PSD

     
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